This explorative international, multi-center, study aims to identify known and novel mutations in patients with bradykinin-mediated recurrent angioedema, by use of buccal swab analysis. We hope this project will spread globally and to improve patient care. It is the follow-up project to IMAGINE, which used dried blood spot analysis and expired in 2023.
IMAGINE 2.0 is a project of the GA²LEN HAEi network of Angioedema Centers of Reference and Excellence (ACARE). The ACARE network encourages all of its member physicians as well as non-ACARE physicians who treat patients with HAE to participate in this project.